After leaving Vietnam with his family in 1975 and grew up in the United States of America, Dustin Tri Nguyen (pronounced "Gwen") went on to establish himself as one of Hollywood's premiere Asian-American actors, having starred on such hit TV shows as "21 Jump Street", "Seaquest DSV", as well as feature films. Of noteworthy is Dustin landing the much-coveted starring role in the critically acclaimed LITTLE FISH opposite Academy Award-winner Cate Blanchett. Dustin plays 'Jonny' Blanchett's love interest in a story that revolves around her 'Tracy' an ex-heroin-addict trying to rebuild her life. The film premiered at the Toronto International Film Festival and went on to become the number-one film in Australia. Along the way, it collected 5 Australian Film Institute Awards and 3 Film Critics Awards. LITTLE FISH then opened in New York to rave reviews. Critics took note of Dustin's performance and transformation into a leading man among the A-list cast. This very performance earned him the 2007 Asian Excellence Award for Best Supporting Actor in a feature film.

In April 2010, Dustin's newly formed production company, Early Risers Media Group, released their first feature film, DE MAI TINH (FOOL FOR LOVE.) This romantic-comedy, in which Dustin wrote and produced and starred in, broke Vietnam's box-office record for an April release, taking on Hollywood films head-to-head, as well as unanimously praised by critics and audience alike.

This past 2009, Dustin was awarded the Vietnamese Golden Lotus Award (Vietnam's Highest Film Award) for Best Actor in the motion picture THE LEGEND IS ALIVE, as well as the Golden Kite Award (Vietnam's Cinema Association) for the very same role. He was also awarded the Golden Rooster (China's most prestigious film award) for Favorite International Actor for this very role. Dustin played Long, a mentally challenged man, whose only wish is to bring his recently deceased mother's ashes to America. Along his journey, Long encounters and reluctantly involves himself with a young girl who has been sold to human traffickers.

In 2008, Dustin starred in Justin Lin's film FINISHING THE GAME, which had premiered at the Sundance Film Festival. In 2006, Dustin starred in his first villain role in the Vietnamese blockbuster THE REBEL, a French-Vietnamese 1920's period action-drama. It marked his first return to Vietnam in 32 years.

In 2000, Dustin's martial arts expertise was showcased when he starred in Levi's Jeans' European "Hero" campaign, which expanded upon his ever-growing international profile. The campaign was uniquely groundbreaking in that it was the first time Levi's had ever used an Asian star in their awarded winning campaigns. For Dustin, it offered the first opportunity to apply his love for the martial arts along with his dramatic training as he collaborated with director Jonathan Glazer (SEXY BEAST, BIRTH) on the fight choreography.